Car slams into the side of a house, killing three people, in Perth WA

Three people have died and another two are in hospital after a car crashed into the side of suburban house in Perth.

Emergency crews were called following reports a car left the road and crashed with the rear wall of a home that backs onto Orrong Rd in Carlisle about 5.10am on Saturday.

Three adults in the vehicle were treated by St John Ambulance paramedics for their critical injuries but sadly died at the scene.

Another two adults who were in the car were taken to Royal Perth Hospital to received treatment for their serious injuries.

Nobody inside the home were injured during the incident.

Drivers are being urged to avoid the area as Orrong Rd in both directions between Francisco St and Archer St remains closed and will be for a number of hours.

Members of the public are also asked to avoid the area as a number of police and emergency resources remain at the scene.